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Article

Pathological and genomic phenotype of second neuroendocrine carcinoma during long-term follow-up after radical radiotherapy for nasopharyngeal carcinoma.

Radiation oncology (London, England) - 11 Oct 2021

Peng Ying-Peng, Liu Qiao-Dan, Lin Yu-Jing, Peng Shun-Li, Wang Rong, Xu Xi-Wei, Wei Wei, Zhong Gui-Hua, Zhou Yu-Ling, Zhang Ya-Qin, Liu Ye, Wang Si-Yang, Hong Hai-Yu, Liu Zhi-Gang

Abstract excerpt

BACKGROUND: Second head and neck neuroendocrine carcinoma (NEC) after radical radiotherapy for nasopharyngeal carcinoma (NPC) treatment is rarely reported. The prognosis of second cancer is poor, and our research focuses on finding a breakthrough in the treatment. In this study, we aimed to investigate clinicopathological characteristics and to identify the genomic landscape of second head and neck NECs. METHODS:...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34635145
DOI: 10.1186/s13014-021-01898-z
PMCID: PMC8504105

Genes

ABL1
COL22A1
DAXX
ELAC2
EPPK1
KMT2C
NOTCH2
POLG
PTEN
RB1
TP53
U2AF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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