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Article

Comparison of sequencing data processing pipelines and application to underrepresented African human populations.

BMC bioinformatics - 9 Oct 2021

Breton Gwenna, Johansson Anna C V, Sjödin Per, Schlebusch Carina M, Jakobsson Mattias

Abstract excerpt

BACKGROUND: Population genetic studies of humans make increasing use of high-throughput sequencing in order to capture diversity in an unbiased way. There is an abundance of sequencing technologies, bioinformatic tools and the available genomes are increasing in number. Studies have evaluated and compared some of these technologies and tools, such as the Genome Analysis Toolkit (GATK) and its "Best Practices"...

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Identifiers

PMID: 34627144
DOI: 10.1186/s12859-021-04407-x
PMCID: PMC8502359

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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