Article
Aberrant expression of MYD88 via RNA-controlling CNOT4 and EXOSC3 in colonic mucosa impacts generation of colonic cancer.
Cancer science - 1 Dec 2021
Tsuda Masumi, Noguchi Misa, Kurai Tsuyoshi, Ichihashi Yuji, Ise Koki, Wang Lei, Ishida Yusuke, Tanino Mishie, Hirano Satoshi, Asaka Masahiro, Tanaka Shinya
Abstract excerpt
In 2020, the worldwide incidence and mortality of colorectal cancer (CRC) were third and second, respectively. As the 5-y survival rate is low when CRC is diagnosed at an advanced stage, a reliable method to predict CRC susceptibility is important for preventing the onset and development and improving the prognosis of CRC. Therefore, we focused on the normal colonic mucosa to investigate changes in gene...
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