IL10 promoter rs6667202 polymorphism is functional in health but not in grade c periodontitis patients: A pilot study.

doi:10.1111/jre.12940

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Article

IL10 promoter rs6667202 polymorphism is functional in health but not in grade c periodontitis patients: A pilot study.

Journal of periodontal research - 1 Jan 2022

Stolf Camila S, Sacramento Catharina M, Paz Hélvis E S, Machado Renato A, Ramos Lucas P, de Oliveira Luciane D, Cogo-Müller Karina, Santamaria Mauro P, Ruiz Karina G S, Casarin Renato C V

Abstract excerpt

BACKGROUND AND OBJECTIVE: Previous studies have demonstrated an association between the IL10 promoter rs6667202 (C > A) single-nucleotide polymorphism (SNP) and grade C, stage 3 or 4 periodontitis (Perio4C) in the Brazilian population, where the altered A allele was detected more frequently in these patients. However, no functional analysis of this variation has yet been performed. Thus, the objective of this...

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PMID: 34611908
DOI: 10.1111/jre.12940

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