Article
Characterization of humoral and SARS-CoV-2 specific T cell responses in people living with HIV.
Nature communications - 5 Oct 2021
Alrubayyi Aljawharah, Gea-Mallorquí Ester, Touizer Emma, Hameiri-Bowen Dan, Kopycinski Jakub, Charlton Bethany, Fisher-Pearson Natasha, Muir Luke, Rosa Annachiara, Roustan Chloe, Earl Christopher, Cherepanov Peter, Pellegrino Pierre, Waters Laura, Burns Fiona, Kinloch Sabine, Dong Tao, Dorrell Lucy, Rowland-Jones Sarah, McCoy Laura E, Peppa Dimitra
Abstract excerpt
There is an urgent need to understand the nature of immune responses against SARS-CoV-2, to inform risk-mitigation strategies for people living with HIV (PLWH). Here we show that the majority of PLWH with ART suppressed HIV viral load, mount a detectable adaptive immune response to SARS-CoV-2. Humoral and SARS-CoV-2-specific T cell responses are comparable between HIV-positive and negative subjects and persist...
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