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Novel Quadruplex PCR for detecting and genotyping mobile colistin resistance genes in human samples.

Diagnostic microbiology and infectious disease - 1 Dec 2021

Hu Shuangfang, Lv Ziquan, Wang Yang, Shen Jianzhong, Ke Yuebin

Abstract excerpt

Since 2016, several mobile colistin resistance (mcr) genes have been identified worldwide. It's worth noting that only mcr-1, mcr-3, mcr-8, and mcr-10 have been reported isolated directly from clinical samples which created greater risk to human health than other mcr gene types. A novel Quadruplex polymerase chain reaction (Quad-PCR) protocol was developed to detect and genotype transferable colistin-resistance...

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Source

Identifiers

PMID: 34610496
DOI: 10.1016/j.diagmicrobio.2021.115419

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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