[Immunogenetic studies in patients with IgM rheumatoid factor negative erosive chronic polyarthritis (c.p.)].

Article

[Immunogenetic studies in patients with IgM rheumatoid factor negative erosive chronic polyarthritis (c.p.)].

Zeitschrift fur Rheumatologie - 1 Jan 2000

Bröll H, Haberhauer G

Abstract excerpt

40 patients with erosive rheumatoid arthritis (RA), 20 of whom were IgM-negative and 20 IgM-positive, were studied prospectively with regard to their association with HLA-B-CREGs (B5-, B8-, B12-, B16-, B27-CREG). We found a highly significant association of IgM-negative RA patients and B5-CREG-antigens (Chi2 = 28.6; p less than 0.001).

Topics

Alleles
Arthritis, Rheumatoid
Chromosome Mapping
Female
Gene Frequency
HLA Antigens
HLA-B Antigens
Humans
Immunoglobulin M
Male
Middle Aged
Rheumatoid Factor

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