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Refinement of microbiota analysis of specimens from patients with respiratory infections using next-generation sequencing

1 Oct 2021

Abstract excerpt

Next-generation sequencing (NGS) technologies have been applied in bacterial flora analysis. However, there is no standardized protocol, and the optimal clustering threshold for estimating bacterial species in respiratory infection specimens is unknown. This study was conducted to investigate the optimal threshold for clustering 16S ribosomal RNA gene sequences into operational taxonomic units (OTUs) by comparing...

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PMID: 34599245
DOI: 10.1038/s41598-021-98985-8

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