The IL-6 rs1800795 and rs1800796 polymorphisms are associated with coronary artery disease risk.

doi:10.1111/jcmm.15246

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

The IL-6 rs1800795 and rs1800796 polymorphisms are associated with coronary artery disease risk.

Journal of cellular and molecular medicine - 1 Jun 2020

Lu Shuai, Wang Ya, Wang Yijun, Hu Jing, Di Wu, Liu Shuangye, Zeng Xiaohui, Yu Guo, Wang Yan, Wang Zhaohui

Abstract excerpt

Studies examining the associations between the interleukin-6 (IL-6) rs1800795 and rs1800796 gene polymorphisms and risk of coronary artery disease (CAD) remain controversial. Our aim was to evaluate the accurately determine role of these two polymorphisms in CAD risk. PubMed, Embase, VIP, Wan fang and China National Knowledge Infrastructure databases were searched. The odds ratios (ORs) and 95% confidence...

Topics

Coronary Artery Disease
Genetic Association Studies
Genetic Predisposition to Disease
Humans
Interleukin-6

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Middle Aged

Nucleic Acid Conformation

Polymorphism, Single Nucleotide

Publication Bias

RNA

Risk Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 32374489
DOI: 10.1111/jcmm.15246
PMCID: PMC7294134

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-32374489-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The IL-6 rs1800795 and rs1800796 polymorphisms are associated with coronary artery disease risk.PMID 32374489Read ↗

IL-6 gene promoter polymorphisms and risk of coronary artery disease in a Chinese population.Semantic proximity Read ↗

Systematic review and meta-analysis of association of polymorphisms in inflammatory cytokine genes with coronary artery disease.Semantic proximity Read ↗

Association of interleukin-6 gene polymorphism with coronary artery disease: an updated systematic review and cumulative meta-analysis.Semantic proximity Read ↗

Association between interleukin 6 and interleukin 16 gene polymorphisms and coronary heart disease risk in a Chinese population.Semantic proximity Read ↗

Genetic polymorphisms of interleukin-6 gene and susceptibility to coronary artery disease in Chinese population: Evidence based on 4582 subjects.Semantic proximity Read ↗

Association of interleukin 6 -174 G/C polymorphism with coronary artery disease and circulating IL-6 levels: a systematic review and meta-analysis.Semantic proximity Read ↗

IL-6 gene polymorphisms and CAD risk: a meta-analysis.Semantic proximity Read ↗

Interleukin-6 (IL-6) -174G/C genomic polymorphism contribution to the risk of coronary artery disease in a Chinese population.Semantic proximity Read ↗

Association of interleukin gene polymorphisms with the risk of coronary artery disease.Semantic proximity Read ↗

Common polymorphisms in the interleukin-6 gene and myocardial infarction risk: a meta-analysis.Semantic proximity Read ↗

Genetic Variant rs1800795 (G>C) in the Interleukin 6 (IL6) Gene and Susceptibility to Coronary Artery Diseases, Type 2 Diabetes, Acute Pancreatitis, Rheumatoid Arthritis, and Bronchial Asthma in Asians: A Comprehensive Meta-Analysis Based on 30154 SubjectsSemantic proximity Read ↗

Influence of interleukin-6 gene -174G>C polymorphism on development of atherosclerosis: a meta-analysis of 50 studies involving 33,514 subjects.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.