Development of anti-Jk3 associated with silenced Kidd antigen expression and a novel single nucleotide variant of the JK gene.

doi:10.21307/immunohematology-2021-015

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Article

Development of anti-Jk3 associated with silenced Kidd antigen expression and a novel single nucleotide variant of the JK gene.

Immunohematology - 1 Sept 2021

Manrai P A, Siddon A J, Hager K M, Hendrickson J E, Keller M A, Tormey C A

Abstract excerpt

Anti-Jk3 is a rare alloantibody to a high-prevalence antigen primarily seen in individuals of Polynesian descent and is associated with a handful of well-established variants of the SLC14A1 gene. We report a case of the Jknull phenotype, associated with formation of anti-Jk3, in a patient of non-Polynesian descent. This patient, a 51-year-old woman self-described as of Jamaican and Scottish ancestry, presented to...

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PMID: 34591379
DOI: 10.21307/immunohematology-2021-015

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