Article
Novel alleles at the JK blood group locus explain the absence of the erythrocyte urea transporter in European families.
British journal of haematology - 1 Feb 2002
Irshaid Nidal M, Eicher Nicole I, Hustinx Hein, Poole Joyce, Olsson Martin L
Abstract excerpt
The Kidd (JK) blood group system is of importance in transfusion medicine. The Jk(null) phenotype is associated with absence of the urea transporter in erythrocytes and moderately reduced ability to concentrate urine. We and others recently reported different molecular alterations in the silenced Jkb-like alleles of Polynesians and Finns, populations with higher Jk(null) frequencies. Here we report novel...
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