Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Histone deacetylase HDAC2 silencing prevents endometriosis by activating the HNF4A/ARID1A axis

29 Sept 2021

Abstract excerpt

Endometriosis is the most major cause of chronic pelvic pain in women of reproductive age. Moreover, the involvement of histone deacetylase 2 (HDAC2) has been identified in endometriosis. However, the specific mechanism of HDAC2 remains to be further elusive. Therefore, this study was designed to explore the mechanism of HDAC2 orchestrating hepatocyte nuclear factor 4α/AT-rich interactive domain 1A (HNF4A/ARID1A)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Endometriosis Research and Treatment
Share to Pregnancy-related medical research
Share to Uterine Myomas and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34586697
DOI: 10.1111/jcmm.16835

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Histone deacetylase HDAC2 silencing prevents endometriosis by activating the HNF4A/ARID1A axisPMID 34586697Read ↗

Vorinostat decrease M2 macrophage polarization through ARID1A6488delG/HDAC6/IL-10 signaling pathway in endometriosis-associated ovarian carcinomaSemantic proximity Read ↗

Repurposing Pan-HDAC Inhibitors for ARID1A-Mutated Ovarian Cancer.Semantic proximity Read ↗

Chromatin remodeling factor ARID2 suppresses hepatocellular carcinoma metastasis via DNMT1-Snail axis.Semantic proximity Read ↗

ARID1A Is Essential for Endometrial Function during Early PregnancySemantic proximity Read ↗

The emerging roles of ARID1A in tumor suppression.Semantic proximity Read ↗

Distinct and overlapping roles of ARID3A and ARID3B in regulating E2F‑dependent transcription via direct binding to E2F target genesSemantic proximity Read ↗

NUCKS1 is Overexpressed in EndometriosisSemantic proximity Read ↗

Endometrial epithelial ARID1A is critical for uterine gland function in early pregnancy establishmentSemantic proximity Read ↗

Down-regulation of ARID1A is sufficient to initiate neoplastic transformation along with epigenetic reprogramming in non-tumorigenic endometriotic cells.Semantic proximity Read ↗

Chromatin remodeling gene<i>ARID2</i>targets cyclin D1 and cyclin E1 to suppress hepatoma cell progressionSemantic proximity Read ↗

The roles of ARID1A in gynecologic cancerSemantic proximity Read ↗

Explore the alterations of downstream molecular pathways caused by ARID1A mutation/knockout in human endometrial cancer cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.