Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Choroideremia Gene Therapy

28 Sept 2021

Abstract excerpt

Introduction Choroideremia is a rare X-linked recessive retinal degeneration of photoreceptors, retinal pigment epithelium (RPE), and choroid that progresses in a centripetal manner.1 Choroideremia results from pathologic genetic variants of the CHM gene on the X chromosome with nearly all being loss-of-function null mutations.1 The CHM gene product, Rab escort protein 1 (REP-1), is expressed in all human cells...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Retinal Development and Disorders
Share to Retinal Diseases and Treatments
Share to Retinopathy of Prematurity Studies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34584056
DOI: 10.1097/iio.0000000000000385

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Choroideremia Gene TherapyPMID 34584056Read ↗

CHOROIDEREMIASemantic proximity Read ↗

Choroideremia: a review of general findings and pathogenesis.Semantic proximity Read ↗

Choroideremia: from genetic and clinical phenotyping to gene therapy and future treatmentsSemantic proximity Read ↗

Choroideremia: molecular mechanisms and therapies.Semantic proximity Read ↗

Choroideremia.Semantic proximity Read ↗

Molecular Therapies for ChoroideremiaSemantic proximity Read ↗

Use of induced pluripotent stem cell models to probe the pathogenesis of Choroideremia and to develop a potential treatmentSemantic proximity Read ↗

Choroideremia: molecular mechanisms and development of AAV gene therapy.Semantic proximity Read ↗

Gene therapy for choroideremia using an adeno-associated viral vector encoding Rab escort protein 1: the REGENERATE open-label trialSemantic proximity Read ↗

Choroideremia gene testingSemantic proximity Read ↗

Efficacy and Safety of Retinal Gene Therapy Using Adeno-Associated Virus Vector for Patients With ChoroideremiaSemantic proximity Read ↗

Association of Messenger RNA Level With Phenotype in Patients With Choroideremia: Potential Implications for Gene Therapy Dose.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.