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Article

Hepatitis B Transmission: Is Vertical Transmission the Major Route in Intermediate Endemic Areas? A Proof-of-Concept Study Based on Mother-Child Genotypes.

The American journal of tropical medicine and hygiene - 27 Sept 2021

Poddar Ujjal, Benjamin Mercilena, Aggarwal Rakesh, Sarangi Aditya Narayan, Mathias Amrita, Yachha Surender Kumar, Srivastava Anshu

Abstract excerpt

The route of hepatitis B transmission is believed to be horizontal in India, though pediatric studies showed mother as source in the majority of chronic HBV (CHB) cases. We aimed at establishing the fact that mother-child transmission is the main route of acquisition by documenting genotypically identical viruses in mother-child pairs. Blood samples of consecutive children (≤ 18 years) with CHB and high DNA (>...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34583333
DOI: 10.4269/ajtmh.21-0283
PMCID: PMC8641309

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