Article
Hepatitis B virus genotypes in children and adolescents in Japan: before and after immunization for the prevention of mother to infant transmission of hepatitis B virus.
Journal of medical virology - 1 Jun 2007
Inui Ayano, Komatsu Haruki, Sogo Tsuyoshi, Nagai Toshiro, Abe Kenji, Fujisawa Tomoo
Abstract excerpt
The genotype distribution of hepatitis B virus (HBV) was investigated in 118 children in Japan. One hundred and sixteen children (98%) had chronic HBV infection, and the remainder had acute hepatitis. Genotyping of HBV was determined by PCR and sequencing analysis in the S gene. Genotype C (86%) was the most frequent, followed by genotype B (9%), D (2.5%), and A (1.0%). Transmission routes of HBV to children were...
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