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Prognostic Roles of BRAF, KIT, NRAS, IGF2R and SF3B1 Mutations in Mucosal Melanomas.

Cells - 27 Aug 2021

Wróblewska Joanna P, Dias-Santagata Dora, Ustaszewski Adam, Wu Cheng-Lin, Fujimoto Masakazu, Selim M Angelica, Biernat Wojciech, Ryś Janusz, Marszalek Andrzej, Hoang Mai P

Abstract excerpt

BACKGROUND: The prognostic value of commonly recurrent mutations remains unclear in mucosal melanomas. METHODS: Clinicopathologic parameters of 214 cases of mucosal melanomas diagnosed in 1989-2020 in several clinical institutions were analyzed. NRAS, KIT, BRAF, IGF2R and SF3B1 mutational analyses by Sanger sequencing and next generation sequencing-based assay were performed in a subset of cases. RESULTS: Of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34571863
DOI: 10.3390/cells10092216
PMCID: PMC8468625

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