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In silico polypharmacology of natural products

31 Mar 2017

Abstract excerpt

Natural products with polypharmacological profiles have demonstrated promise as novel therapeutics for various complex diseases, including cancer. Currently, many gaps exist in our knowledge of which compounds interact with which targets, and experimentally testing all possible interactions is infeasible. Recent advances and developments of systems pharmacology and computational (in silico) approaches provide...

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PMID: 28460068
DOI: 10.1093/bib/bbx045

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