Article
Use of a Sodium-Glucose Cotransporter 2 Inhibitor, Empagliflozin, in a Patient with Rabson-Mendenhall Syndrome.
Hormone research in paediatrics - 1 Jan 2021
Dos Santos Sarah Simaan, Ramaldes Luana Aparecida, Gabbay Monica Andrade Lima, Moises Regina Celia Santiago, Dib Sergio Atala
Abstract excerpt
INTRODUCTION: Among the insulin resistance syndromes that lead to diabetes mellitus in young people, Rabson-Mendenhall syndrome (RMS; OMIM # 262190) is an autosomal recessive inherited disease caused by an insulin receptor mutation (INSR; 147,670). Due to the rarity and complexity of the disease, we have few therapeutic alternatives other than insulin with clinical studies with robust evidence. Some reports...
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