Article
The role of genotype and diet in shaping gut microbiome in a genetic vitamin A deficient mouse model.
Journal of genetics and genomics = Yi chuan xue bao - 1 Feb 2022
Xu Jun, Zhang Jie-Ni, Sun Bo-Hui, Liu Qing, Ma Juan, Zhang Qian, Liu Yong-Xin, Chen Ning, Chen Feng
Abstract excerpt
Multifactors have been reported to affect the gut microbiome, including genotype, age, diet, and nutrition. However, few reports have investigated the relative capacity of different factors to shape the gut microbiome in a single study. Our design used a genetic vitamin A-deficient mouse model, the Rbp4-/- mouse, feeding with the low vitamin A diets at different ages of initiation (4 or 7 weeks) for 28 days....
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