Article
Immune signatures of bone marrow cells can independently predict prognosis in patients with myelodysplastic syndrome.
British journal of haematology - 1 Jan 2022
Wang Yu-Hung, Lin Chien-Chin, Yao Chi-Yuan, Hsu Chia-Lang, Tsai Cheng-Hong, Hou Hsin-An, Chou Wen-Chien, Tien Hwei-Fang
Abstract excerpt
Increasing evidence supports the role of the immune microenvironment and associated signalling in the pathogenesis of myelodysplastic syndromes (MDS). Nevertheless, the clinical relevancy of immune signals in patients with MDS remains elusive. To address this, we used single-sample gene-set enrichment analysis to score immune signatures of bone marrow (BM) samples from 176 patients with primary MDS. Enhanced...
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