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Differences in faecal microbiome composition between adult patients with UCD and PKU and healthy control subjects

8 Sept 2021

Abstract excerpt

Urea cycle disorders (UCDs) are a group of rare inherited metabolic diseases causing hyperammonemic encephalopathy. Despite intensive dietary and pharmacological therapy, outcome is poor in a subset of UCD patients. Reducing ammonia production by changing faecal microbiome in UCD is an attractive treatment approach. We compared faecal microbiome composition of 10 UCD patients, 10 healthy control subjects and 10...

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PMID: 34527515
DOI: 10.1016/j.ymgmr.2021.100794

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