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Article

Clinical outcomes of patients taking first-generation EGFR-TKIs may predict the benefits afforded by osimertinib in EGFR T790M-mutant NSCLC patients.

International journal of clinical practice - 1 Dec 2021

Meng Hongxue, Huang Lan, Wang Jiahui, Zhou Yingxu, Wang Meng, Yang Zhaoyang, Hong Xuan

Abstract excerpt

BACKGROUND: Epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) are widely used to treat patients with EGFR-mutated non-small cell lung cancers (NSCLCs). The association between the clinical outcomes of patients on first-line EGFR-TKIs and the efficacy of osimertinib as second-line treatment has not been previously assessed. This is our topic here. PATIENTS AND METHODS: We retrospectively...

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Identifiers

PMID: 34525256
DOI: 10.1111/ijcp.14877

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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