Article
A consensus on the role of osimertinib in non-small cell lung cancer from the AME Lung Cancer Collaborative Group
1 Jul 2018
Abstract excerpt
Abstract: The first- and second-generation epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) have brought substantial clinical benefit to patients with advanced non-small cell lung cancer (NSCLC) and sensitizing EGFR mutation. However, acquired resistance is inevitable since the vast majority of patients experience disease relapse within ~1–2 years. Osimertinib is a novel irreversible,...
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