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Article

Impact of risk factors for major cardiovascular diseases: a comparison of life-time observational and Mendelian randomisation findings.

Open heart - 1 Sept 2021

Lind Lars, Ingelsson Martin, Sundstrom Johan, Ärnlöv Johan

Abstract excerpt

BACKGROUND: This study compared the strength and causality of associations between major risk factors for cardiovascular disease (CVD) and the four major CVDs: myocardial infarction, ischaemic stroke, heart failure and atrial fibrillation. Both a long-term follow-up in an observational cohort and Mendelian randomisation (MR) were used for this aim. METHODS: In the Uppsala Longitudinal Study of Adult Men study,...

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Identifiers

PMID: 34518286
DOI: 10.1136/openhrt-2021-001735
PMCID: PMC8438838

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