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Article

Optimal echocardiographic assessment of myocardial dysfunction for arrhythmic risk stratification in phospholamban mutation carriers.

European heart journal. Cardiovascular Imaging - 20 Oct 2022

Taha Karim, Verstraelen Tom E, de Brouwer Remco, de Bruin-Bon Rianne H A C M, Cramer Maarten J, Te Rijdt Wouter P, Bouma Berto J, de Boer Rudolf A, Doevendans Pieter A, Asselbergs Folkert W, Wilde Arthur A M, van den Berg Maarten P, Teske Arco J

Abstract excerpt

AIMS: Phospholamban (PLN) p.Arg14del mutation carriers are at risk of developing malignant ventricular arrhythmias (VAs) and/or heart failure. Currently, left ventricular ejection fraction (LVEF) plays an important role in risk assessment for VA in these individuals. We aimed to study the incremental prognostic value of left ventricular mechanical dispersion (LVMD) by echocardiographic deformation imaging for...

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Identifiers

PMID: 34516619
DOI: 10.1093/ehjci/jeab178
PMCID: PMC9584619

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