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Article

Submucosal gland duct adenoma of the esophagus: expanding the morphologic spectrum of a rare tumor entity.

Virchows Archiv : an international journal of pathology - 1 Aug 2026

Hua Hongjin, Ding Ying, Zhang Jinxing, Hu Die, Zhang Yue, Zhao Sha, Si Xinmin, Zhang Zhihong, Li Hai

Abstract excerpt

Esophageal submucosal gland duct adenoma (ESGDA) is an extremely rare benign tumor originating from the esophageal ducts, resembling sialadenoma papilliferum (SP) of the minor salivary glands. However, the clinicopathological and molecular features of ESGDA remain incompletely characterized. We performed a multicenter, retrospective study aimed to elucidate the clinicopathological and molecular mechanisms...

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Adenoma
Aged
Biomarkers, Tumor
Esophageal Neoplasms
BRAF gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Proto-Oncogene Proteins B-raf

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PMID: 41324652
DOI: 10.1007/s00428-025-04344-7

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BRAF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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