Article
Homozygosity of short VNTR lengths in the CEL gene may confer susceptibility to idiopathic chronic pancreatitis.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] - 1 Oct 2021
Mao Xiao-Tong, Deng Shun-Jiang, Kang Rui-Lin, Wang Yuan-Chen, Li Zhao-Shen, Zou Wen-Bin, Liao Zhuan
Abstract excerpt
OBJECTIVE: The carboxyl-ester lipase (CEL) gene contains a variable number of tandem repeats (VNTR) region. It remains unclear whether the number of repeats in the CEL VNTR is related to the risk of pancreatic diseases. The aim of this study was to investigate whether CEL VNTR length is associated with idiopathic chronic pancreatitis (ICP), alcoholic chronic pancreatitis (ACP), or pancreatic cancer in a cohort of...
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