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Article

Direct sequencing of measles virus complete genomes in the midst of a large-scale outbreak.

PloS one - 1 Jan 2021

Bucris Efrat, Indenbaum Victoria, Azar Roberto, Erster Oran, Haas Eric, Mendelson Ella, Zuckerman Neta S

Abstract excerpt

Measles outbreaks escalated globally despite worldwide elimination efforts. Molecular epidemiological investigations utilizing partial measles virus (MeV) genomes are challenged by reduction in global genotypes and low evolutionary rates. Greater resolution was reached using MeV complete genomes, however time and costs limit the application to numerous samples. We developed an approach to unbiasedly sequence...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34506497
DOI: 10.1371/journal.pone.0255663
PMCID: PMC8432851

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