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Article

Single-cell analysis of a tumor-derived exosome signature correlates with prognosis and immunotherapy response

8 Sept 2021

Abstract excerpt

BACKGROUND: Tumor-derived exosomes (TEXs) are involved in tumor progression and the immune modulation process and mediate intercellular communication in the tumor microenvironment. Although exosomes are considered promising liquid biomarkers for disease diagnosis, it is difficult to discriminate TEXs and to develop TEX-based predictive biomarkers. METHODS: In this study, the gene expression profiles and clinical...

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PMID: 34496872
DOI: 10.1186/s12967-021-03053-4

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