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CD19-directed CAR T-cell therapy for treatment of primary CNS lymphoma

7 Sept 2021

Abstract excerpt

CD19-directed chimeric antigen receptor (CD19CAR) T-cell therapy has been successful in treating several B-cell lineage malignancies, including B-cell non-Hodgkin lymphoma (NHL). This modality has not yet been extended to NHL manifesting in the central nervous system (CNS), primarily as a result of concerns for potential toxicity. CD19CAR T cells administered IV are detectable in cerebrospinal fluid (CSF),...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 34492703
DOI: 10.1182/bloodadvances.2020004106

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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