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Disrupting biological sensors of force promotes tissue regeneration in large organisms

6 Sept 2021

Abstract excerpt

Tissue repair and healing remain among the most complicated processes that occur during postnatal life. Humans and other large organisms heal by forming fibrotic scar tissue with diminished function, while smaller organisms respond with scarless tissue regeneration and functional restoration. Well-established scaling principles reveal that organism size exponentially correlates with peak tissue forces during...

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PMID: 34489407
DOI: 10.1038/s41467-021-25410-z

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