Article
[Analysis of DNAH1 gene variant in two infertile males with multiple morphological abnormalities of sperm flagella].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 10 Sept 2021
Feng Ke, Wan Feng, Xia Yanqing, Yang Ke, Qu Xiaowei, Xia Song, Guo Haibin, Zhang Cuilian, Wu Dong
Abstract excerpt
OBJECTIVE: To explore the clinical feature and gene variant for two cases of primary male infertility caused by severe asthenospermia and to analyze the etiology of the disease. METHODS: Genomic DNA of peripheral blood samples of patients and their parents was extracted and gene variant analysis of the patients was conducted by using whole exome sequencing. Suspected pathogenic variant was verified by Sanger...
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