Article
Maternal and offspring genetic risk score analyses of fetal alcohol exposure and attention-deficit hyperactivity disorder risk in offspring.
Alcoholism, clinical and experimental research - 1 Oct 2021
Haan Elis, Sallis Hannah M, Ystrom Eivind, Njølstad Pål Rasmus, Andreassen Ole A, Reichborn-Kjennerud Ted, Munafò Marcus R, Havdahl Alexandra, Zuccolo Luisa
Abstract excerpt
BACKGROUND: Studies investigating the effects of prenatal alcohol exposure on childhood attention-deficit hyperactivity disorder (ADHD) symptoms using conventional observational designs have reported inconsistent findings, which may be affected by unmeasured confounding and maternal and fetal ability to metabolize alcohol. We used genetic variants from the alcohol metabolizing genes, alcohol dehydrogenase (ADH)...
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