Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

D614G mutation eventuates in all VOI and VOC in SARS-CoV-2: Is it part of the positive selection pioneered by Darwin?

31 Aug 2021

Abstract excerpt

Recently, several emerging variants of SARS-CoV-2 have originated from the Wuhan strain and spread throughout the globe within one and a half years. One mutation, D614G, is very prominent in all VOI and VOC in SARS-CoV-2. This mutation might help to increase the viral fitness in all emerging variants where the mutation is present. With the help of this mutation (D614G), the SARS-CoV-2 variants have gained viral...

Source

Identifiers

PMID: 34484868
DOI: 10.1016/j.omtn.2021.07.011

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

D614G mutation eventuates in all VOI and VOC in SARS-CoV-2: Is it part of the positive selection pioneered by Darwin?PMID 34484868Read ↗

The Yin and Yang of SARS-CoV-2 Mutation and Evolution.Semantic proximity Read ↗

The D614G mutation helps to increase the transmissibility and reduce the virulence of SARS-CoV-2 variants through natural selection.Semantic proximity Read ↗

Intra- vs. inter-host evolution of SARS-CoV-2 driven by uncorrelated selection - The evolution thwartedSemantic proximity Read ↗

Evolutionary Mechanisms of the Emergence of the Variants of Concern of SARS-CoV-2Semantic proximity Read ↗

Host-dependent C-to-U RNA editing in SARS-CoV-2 creates novel viral genes with optimized expressibility.Semantic proximity Read ↗

An evolutionary theory on virus mutation in COVID-19.Semantic proximity Read ↗

De novo emergence of the mutation E484K in a SARS-CoV-2 B.1.1.7 lineage variant.Semantic proximity Read ↗

An in-silico study on SARS-CoV-2: Its compatibility with human tRNA pool, and the polymorphism arising in a single lineage over a monthSemantic proximity Read ↗

Natural selection plays a significant role in governing the codon usage bias in the novel SARS-CoV-2 variants of concern (VOC)Semantic proximity Read ↗

Within-Host and Between-Host Evolution in SARS-CoV-2-New Variant's Source.Semantic proximity Read ↗

Evolutionary shift from purifying selection towards divergent selection of SARS-CoV2 favors its invasion into multiple human organs.Semantic proximity Read ↗

Positive selection as a key player for SARS-CoV-2 pathogenicity: Insights into ORF1ab, S and E genesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.