Article
Application of Raman spectroscopy for characterization of the functional polarization of macrophages into M1 and M2 cells.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy - 15 Jan 2022
Ribeiro Ana Rúbia Batista, Silva Elaine Cristina Oliveira, Araújo Polliane Maria Cavalcante, Souza Samuel Teixeira, Fonseca Eduardo Jorge da Silva, Barreto Emiliano
Abstract excerpt
Macrophages are key cells in the immune inflammatory response that can be differentiated into M1 and M2 phenotypes. Polarization has a critical therapeutic value, especially in diseases in which an M1/M2 imbalance plays a pathophysiological role. Raman spectroscopy has proven to be a promising bioanalytical technique for discriminating different cell types. However, to our knowledge, its application to identify...
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