Article
Verification of immunology-related genetic associations in BPD supports ABCA3 and five other genes.
Pediatric research - 1 Jul 2022
Blume Felix, Kirsten Holger, Ahnert Peter, Chakraborty Trinad, Gross Arnd, Horn Katrin, Toliat Mohammad Reza, Nürnberg Peter, Westenfelder Eva-Maria, Goepel Wolfgang, Scholz Markus
Abstract excerpt
BACKGROUND: Inflammatory processes are key drivers of bronchopulmonary dysplasia (BPD), a chronic lung disease in preterm infants. In a large sample, we verify previously reported associations of genetic variants of immunology-related genes with BPD. METHODS: Preterm infants with a gestational age ≤32 weeks from PROGRESS and the German Neonatal Network (GNN) were included. Through a consensus case/control...
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