Article
Exome sequencing and pathway analysis for identification of genetic variability relevant for bronchopulmonary dysplasia (BPD) in preterm newborns: A pilot study.
Clinica chimica acta; international journal of clinical chemistry - 7 Dec 2015
Carrera Paola, Di Resta Chiara, Volonteri Chiara, Castiglioni Emanuela, Bonfiglio Silvia, Lazarevic Dejan, Cittaro Davide, Stupka Elia, Ferrari Maurizio, Somaschini Marco
Abstract excerpt
BACKGROUND: Bronchopulmonary dysplasia (BPD) is the most common chronic lung disease in infancy, affecting preterm children with low birth weight. The disease has a multifactorial aetiology with a significant genetic component; until now published association studies have identified several candidate genes but only few of these data has been replicated. In this pilot study, we approached exome sequencing aimed at...
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