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CD4+ T cell and M2 macrophage infiltration predict dedifferentiated liposarcoma patient outcomes

1 Aug 2021

Abstract excerpt

Background Dedifferentiated liposarcoma (DDLPS) is one of the most common soft tissue sarcoma subtypes and is devastating in the advanced/metastatic stage. Despite the observation of clinical responses to PD-1 inhibitors, little is known about the immune microenvironment in relation to patient prognosis. Methods We performed a retrospective study of 61 patients with DDLPS. We completed deep sequencing of the...

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PMID: 34465597
DOI: 10.1136/jitc-2021-002812

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