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Article

Estetrol and Mammary Gland: Friends or Foes?

31 Aug 2021

Abstract excerpt

Estrogens have pleiotropic effects on many reproductive and non-reproductive tissues and organs including the mammary gland, uterus, ovaries, vagina, and endothelium. Estrogen receptor α functions as the principal mediator of estrogenic action in most of these tissues. Estetrol (E4) is a native fetal estrogen with selective tissue actions that is currently approved for use as the estrogen component in a combined...

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PMID: 34463898
DOI: 10.1007/s10911-021-09497-0

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