Article
Clinical use of selective estrogen receptor modulators and down regulators with the main focus on breast cancer.
Minerva ginecologica - 1 Dec 2009
Baumann C K, Castiglione-Gertsch M
Abstract excerpt
Selective estrogen receptor modulators (SERMs) and selective estrogen down regulators (SERDs) act as estrogen receptor (ER) agonists or antagonist depending on the targeted tissue and the specific configuration of the used SERM or SERD. Effects on bone, endometrium and breast cancer are of interest. Endocrine treatments have been used in breast cancer since the end of the 19th century. In the second part of the...
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