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Article

Protein Nucleotidylylation in +ssRNA Viruses

5 Aug 2021

Abstract excerpt

Nucleotidylylation is a post-transcriptional modification important for replication in the picornavirus supergroup of RNA viruses, including members of the Caliciviridae, Coronaviridae, Picornaviridae and Potyviridae virus families. This modification occurs when the RNA-dependent RNA polymerase (RdRp) attaches one or more nucleotides to a target protein through a nucleotidyl-transferase reaction. The most...

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PMID: 34452414
DOI: 10.3390/v13081549

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