Article
Is high vitamin B12 status a cause of lung cancer?
International journal of cancer - 15 Sept 2019
Fanidi Anouar, Carreras-Torres Robert, Larose Tricia L, Yuan Jian-Min, Stevens Victoria L, Weinstein Stephanie J, Albanes Demetrius, Prentice Ross, Pettinger Mary, Cai Qiuyin, Blot William J, Arslan Alan A, Zeleniuch-Jacquotte Anne, McCullough Marjorie L, Le Marchand Loic, Wilkens Lynne R, Haiman Christopher A, Zhang Xuehong, Stampfer Meir J, Smith-Warner Stephanie A, Giovannucci Edward, Giles Graham G, Hodge Allison M, Severi Gianluca, Johansson Mikael, Grankvist Kjell, Langhammer Arnulf, Brumpton Ben M, Wang Renwei, Gao Yu-Tang, Ericson Ulrika, Bojesen Stig E, Arnold Susanne M, Koh Woon-Puay, Shu Xiao-Ou, Xiang Yong-Bing, Li Honglan, Zheng Wei, Lan Qing, Visvanathan Kala, Hoffman-Bolton Judith, Ueland Per M, Midttun Øivind, Caporaso Neil E, Purdue Mark, Freedman Neal D, Buring Julie E, Lee I-Min, Sesso Howard D, Michael Gaziano J, Manjer Jonas, Relton Caroline L, Hung Rayjean J, Amos Chris I, Johansson Mattias, Brennan Paul
Abstract excerpt
Vitamin B supplementation can have side effects for human health, including cancer risk. We aimed to elucidate the role of vitamin B12 in lung cancer etiology via direct measurements of pre-diagnostic circulating vitamin B12 concentrations in a nested case-control study, complemented with a Mendelian randomization (MR) approach in an independent case-control sample. We used pre-diagnostic biomarker data from 5183...
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