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Article

MIR22HG inhibits breast cancer progression by stabilizing LATS2 tumor suppressor.

Cell death & disease - 26 Aug 2021

Deng Xiaochong, Ye Danrong, Hua Kaiyao, Song Hongming, Luo Qifeng, Munankarmy Amik, Liu Diya, Zhou Baian, Zheng Wenfang, Zhou Xiqian, Ji Changle, Wang Xuehui, Yu Yunhe, Fang Lin

Abstract excerpt

The long noncoding RNA called MIR22 host gene (MIR22HG) was previously identified as a tumor suppressor in several cancers. However, the biological function of MIR22HG in breast cancer remains unknown. In this study, we aimed to determine the function and molecular mechanism of MIR22HG in breast cancer progression using transcriptomics and biotechnological techniques. Our results showed that MIR22HG expression...

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Identifiers

PMID: 34446703
DOI: 10.1038/s41419-021-04105-9
PMCID: PMC8390479

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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