Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phosphoproteomics Identifies Significant Biomarkers Associated with the Proliferation and Metastasis of Prostate Cancer.

Toxins - 9 Aug 2021

Xu Rongfang, Chen Yan, Wang Zijun, Zhang Changxin, Dong Xiaoping, Yan Yujie, Wang Ying, Zeng Yong, Chen Ping

Abstract excerpt

The spider peptide toxins HNTX-III and JZTX-I are a specific inhibitor and activator of TTX-S VGSCs, respectively. They play important roles in regulating MAT-LyLu cell metastasis in prostate cancer. In order to identify key biomarkers involved in the regulation of MAT-LyLu cell metastasis, iTRAQ-based quantitative phosphoproteomics analysis was performed on cells treated with HNTX-III, JZTX-I and blank. A total...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Movement
Share to Cell Proliferation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Databases, Factual

Share to Peptides

Share to Phosphoproteins

Share to Prostatic Neoplasms

Share to Protein Interaction Maps

Share to Proteomics

Source

Open in PubMed Open full text

Identifiers

PMID: 34437425
DOI: 10.3390/toxins13080554
PMCID: PMC8402417

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phosphoproteomics Identifies Significant Biomarkers Associated with the Proliferation and Metastasis of Prostate Cancer.PMID 34437425Read ↗

Prostate cancer cell-derived exosomes ZNF667-AS1 reduces TGFBR1 mRNA stability to inhibit Treg expansion and DTX resistance by binding to U2AF1Semantic proximity Read ↗

Comparative Secretome Profiling and Mutant Protein Identification in Metastatic Prostate Cancer Cells by Quantitative Mass Spectrometry-based ProteomicsSemantic proximity Read ↗

HA/CD44 Regulates the T Helper 1 Cells Differentiation by Activating Annexin A1/Akt/mTOR Signaling to Drive the Pathogenesis of EAPSemantic proximity Read ↗

STK10 knockout inhibits cell migration and promotes cell proliferation via modulating the activity of ERM and p38 MAPK in prostate cancer cellsSemantic proximity Read ↗

GATA2 as a potential metastasis-driving gene in prostate cancerSemantic proximity Read ↗

The TβRI promotes migration and metastasis through thrombospondin 1 and ITGAV in prostate cancer cellsSemantic proximity Read ↗

Phospho-proteomic analysis of the effect of merecidin inhibiting the human lung adenocarcinoma A549 cellsSemantic proximity Read ↗

Proteomics Analysis of Formalin Fixed Paraffin Embedded Tissues in the Investigation of Prostate CancerSemantic proximity Read ↗

Integrative analysis of the ST6GALNAC family identifies GATA2-upregulated ST6GALNAC5 as an adverse prognostic biomarker promoting prostate cancer cell invasionSemantic proximity Read ↗

SFMBT2 (Scm-like with four mbt domains 2) negatively regulates cell migration and invasion in prostate cancer cellsSemantic proximity Read ↗

Integrated analysis reveals FOXA1 and Ku70/Ku80 as targets of ivermectin in prostate cancerSemantic proximity Read ↗

Phospho-proteomic analysis of the effect of merecidin inhibiting the human lung adenocarcinoma A549 cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.