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Article

Cellular mechanisms of connexin-based inherited diseases.

Trends in cell biology - 1 Jan 2022

Laird Dale W, Lampe Paul D

Abstract excerpt

The 21-member connexin gene family exhibits distinct tissue expression patterns that can cause a diverse array of over 30 inherited connexin-linked diseases ranging from deafness to skin defects and blindness. Intriguingly, germline mutations can cause disease in one tissue while other tissues that abundantly express the mutant connexin remain disease free, highlighting the importance of the cellular context of...

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Identifiers

PMID: 34429228
DOI: 10.1016/j.tcb.2021.07.007
PMCID: PMC8688313

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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