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Resistance training rejuvenates the mitochondrial methylome in aged human skeletal muscle

23 Aug 2021

Abstract excerpt

Resistance training (RT) dynamically alters the skeletal muscle nuclear DNA methylome. However, no study has examined if RT affects the mitochondrial DNA (mtDNA) methylome. Herein, ten older, Caucasian untrained males (65 ± 7 y.o.) performed six weeks of full-body RT (twice weekly). Body composition and knee extensor torque were assessed prior to and 72 h following the last RT session. Vastus lateralis (VL)...

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PMID: 34423880
DOI: 10.1096/fj.202100873rr

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