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Identification of PDK4 as Hub Gene for Diabetic Nephropathy Using Co-Expression Network Analysis

1 Jan 2023

Abstract excerpt

INTRODUCTION: Diabetic nephropathy (DN) is related to type 1 and type 2 diabetes. They are the leading cause of end-stage renal disease, but the underling specific pathogenesis of DN is not yet clear. Our study was conducted to explore how DN changed the transcriptome profiles in the kidney. METHODS: The gene expression profile of microdissected glomeruli of 41 type 2 DN patients and 20 healthy controls were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37385224
DOI: 10.1159/000531288

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