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BCG Vaccine Derived Peptides Induce SARS-CoV-2 T Cell Cross-Reactivity

5 Aug 2021

Abstract excerpt

Epidemiological studies and clinical trials suggest Bacillus Calmette-Guérin (BCG) vaccine has protective effects against coronavirus disease 2019 (COVID-19). There are now over 30 clinical trials evaluating if BCG vaccination can prevent or reduce the severity of COVID-19. However, the mechanism by which BCG vaccination can induce severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-specific T cell...

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PMID: 34421902
DOI: 10.3389/fimmu.2021.692729

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