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Article

Heterologous vaccine interventions: boosting immunity against future pandemics

31 May 2021

Abstract excerpt

While vaccines traditionally have been designed and used for protection against infection or disease caused by one specific pathogen, there are known off-target effects from vaccines that can impact infection from unrelated pathogens. The best-known non-specific effects from an unrelated or heterologous vaccine are from the use of the Bacillus Calmette-Guérin (BCG) vaccine, mediated partly through trained...

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PMID: 34058986
DOI: 10.1186/s10020-021-00317-z

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