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Hepadnaviral Lymphotropism and Its Relevance to HBV Persistence and Pathogenesis

6 Aug 2021

Abstract excerpt

Since the discovery of hepatitis B virus (HBV) over five decades ago, there have been many independent studies showing presence of HBV genomes in cells of the immune system. However, the nature of HBV lymphotropism and its significance with respect to HBV biology, persistence and the pathogenesis of liver and extrahepatic disorders remains underappreciated. This is in contrast to studies of other viral pathogens...

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PMID: 34421849
DOI: 10.3389/fmicb.2021.695384

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